Abstract: The purpose of this study is to evaluate the risk factors for open-angle glaucoma
progression. Material and methods: The study enrolled 302 patients diagnosed with primary
open-angle glaucoma treated in Eye Hospital - Varna. For the evaluation were used
sociological and clinical methods. SPSS v. 20.0 was used for variation, dispersion,
correlation, and risk assessment analysis. Results and discussions: From the analyses and
comparisons of the results with the other authors, we determined the risk profile of our
patients for progression of POAG. The following factors have been identified as being at risk
for POAG progression: demographic factors (over 60 years of age), comorbidity, ocular
factors (central corneal thickness, pseudoexfoliative syndrome, IOP, decreased sensitivity)
and treatment. Most of our patients were classified in the high-risk group of patients with a
risk assessment of over 15% for disease progression within 5 years at 27.20% for both eyes,
with a risk of progression above 20% at 27.80%; over 33% of the risk was found in 23.80% of
the patients studied. With minimal risk (4%) for both eyes there are only 8.60% of
respondents. High risk for disease progression of over 15% within the 5-year period is
characterized by 75.7% of the patients with an initially incorrect grade of right eye and
80.6% of the patients with an initially incorrectly specified stage of left eye. Conclusions:
Proper diagnose and treatment are the basis for controlling vision loss and preventing
blindness in patients with POAG.
Keywords: POAG, risk factors, progression, risk profile.

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